Formulation Scientist, Exploratory Biopharmaceutics

Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more:careers.bms.com/working-with-us .

Drug Product Development (DPD)
Our Drug Product Development team is committed to CMC design, development, and commercialization of innovative drug products to improve patient lives. We leverage the best people, collaboration, and cutting-edge innovation to achieve this commitment. BMS's internal engine of innovation includes unrivaled industry leading expertise in CMC development of small molecules, protein biotherapeutics, protein degraders, and other therapeutic modalities. We collaborate closely with our colleagues in R&D and Commercial to design our drug products. Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope.

Position Summary
The laboratory-based position will be in the Exploratory Biopharmaceutics (EB) group within the Drug Product Development function. In EB, you will have the ability to impact the lives of patients by working with multi-disciplinary research teams to help in developing novel, efficacious and safe therapeutic molecules. EB is looking for a Scientist with a desire to contribute in the fast-paced early development matrix environment by supporting pre-formulation, physico-chemical characterization, and formulation development of oral and parenteral dosage forms for new small molecule drug candidates in support of preclinical and clinical studies.

The candidate is expected to exhibit a growth mindset and develop expertise in biopharmaceutics and formulation development, represent EB on drug product project teams, execute experiments to deliver knowledge to product development teams.

Key Responsibilities
Key member of a dynamic scientifically driven team, dedicated to the design, development, and characterization of small molecule drug product formulations.
Perform physico-chemical characterization and pre-formulation activities to inform early-stage risk assessment and formulation strategy
Identify, evaluate, and recommend novel drug delivery technologies to develop medicines that provide a better experience for our patients
Develop oral and parenteral formulations to support clinical and preclinical studies.
Collaborate with cross-functional team members to develop and optimize formulations and support technology transfer to CMOs and/or other sites for manufacturing and scale up activities.
Develop experimental protocols and execute in vitro biorelevant dissolution studies for NCEs and drug products.
Prepare technical reports, batch records, SOPs, manuscripts, and oral presentations as required.
Support preparation of CMC regulatory documents.
Support departmental initiatives for assigned projects and methodologies.
Maintain safety, regulatory, and compliance standards as they relate to the development of pharmaceuticals.

Qualifications & Experience:
Degree in Pharmaceutical Science, Pharmaceutics, Pharmaceutical Chemistry, Chemical Engineering, or related discipline; Ph.D. with 0-2 years industrial or post-doc experience, M.S. with 2+ years industrial experience or B.S. with 5+ years industrial experience.
Comprehensive knowledge and understanding of physical pharmacy, fundamentals of pre-formulation, chemistry, stability, and fundamental principles of pharmaceutical science essential for the development of oral and injectable dosage forms.
Hands on experience with analytical tools including HPLC and dissolution apparatus preferred.
Hands on experience in formulation development, pharmaceutical processing related to drug product development preferred.
Experience with designing and developing novel delivery technologies is desired, such as lipid-based drug delivery systems (SMEDDS/SNEDDS), gastro-retentive formulations, particulate systems (nano or micro), hydrogel depots, targeted drug delivery, etc.
Demonstrated problem-solving and troubleshooting skills.
Strong verbal and written communication skills.
Strong interpersonal skills demonstrating effectiveness as a team player on multidisciplinary teams resourced in a flexible and global environment is required.

#GPSProdDev

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as "Transforming patients' lives through science™ ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
BMS has a diverse occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplaceaccommodations/adjustmentsand ongoing support in their roles. Applicants can request a reasonable workplaceaccommodation/adjustmentprior to accepting a job offer. If you require reasonableaccommodations/adjustmentsin completing this application, or in any part of the recruitment process, direct your inquiries ******. Visitcareers.bms.com/eeo-accessibilityto access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information:https://careers.bms.com/california-residents/

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