Core Facility Research Specialist

Full job description The Holden Comprehensive Cancer Center has an exciting opportunity for a Core Facility Research Specialist to support the daily operation of scientific services in the Human Immunology Core. This position will work collaboratively with the Faculty Director and Technical Director for the Human Immunology Core to support translational work and clinical trials at the Holden Comprehensive Cancer Center and the Carver College of Medicine. The Human Immunology Core provides correlative science support for clinical trials testing novel treatments for cancer and other immunological diseases. The techniques used in this core include multi-color flow cytometric analysis of human immune cell phenotypes, measurements of cytokine levels in various clinical samples through techniques such as ELISA and ELISpot, and measurement of autoantibody levels. The Human Immunology Core has recently acquired the capacity for multicolor imaging of tissue samples. The individual in this position will provide day-to-day experimental support and expertise of the Human Immunology Core, with a special focus on developing and optimizing panels for multiplex tissue imaging and performing multiplex imaging experiments for both human and mouse tissue.
Duties to include:
Specialized Services/Application of Research Protocols: Work closely with researchers, investigators, and other core personnel in conducting and/or developing highly technical and specialized scientific research procedures and experiments Perform established research activities based upon protocols developed by Core Directors or other core staff Develop and optimize protocols for multiplex tissue imaging system using the CellScapeä by Canopy Biosciences Assist in the management of the storage, accessibility, and dissemination of data produced by experiments Certify, maintain, and calibrate equipment used in core Record and monitor all supplies used for experiments as well as time spent processing samples, acquiring, and analyzing data Maintain detailed and accurate laboratory notebooks describing purpose, experimental procedures, observations, conclusions, and next steps for each project/experiment Execute and maintain safe laboratory practices and procedures Provide experimental assistance and expertise to other core personnel when needed Provide customer communication, order processing, shipping, and billing Literature Review/Data Analysis: Investigate and perform critical analysis of current literature Perform advanced data analysis for researchers using specialized data analysis software and generate figures for publication Educate, Train, and Consult Provide advanced education, training, and consultation to core facility users and staff on highly specialized equipment or technology Provide advice and guidance to core users, including troubleshooting techniques Review method sections of research papers related to core facility's specialty to be submitted for publication Facilities, Equipment, and Information Management Coordinate and manage equipment and facilities with Core users Perform periodic preventative maintenance on facility instrumentation by servicing, calibrating, and checking equipment for proper function. Troubleshoot equipment failures, procure repair parts, implement repairs, supervise field service engineers, and test equipment for proper function following repairs Maintain the facility computer systems and specialized instrument control and analysis software, facility data server, researchers' data server accounts, data backup and archiving, and reservation accounts Remain current on emerging techniques, software programs, and instrumentation in field of expertise Evaluate and develop new data analysis techniques of methodology Administrative and Financial Responsibility for Fee Service Operation Perform administrative duties as needed Collect and analyze variables to determine appropriate service charges and facility use data for reports UI Health Care Core Values (WE CARE) W elcoming
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SUPERVISION RECEIVED: Supervision provided by the Faculty Director of Immunology Core
SUPERVISION EXERCISED: None
The department intends to hire for one position from either Core Facility Research Professional, requisition ******** or Core Research Facility Specialist, requisition ******** , based on the qualifications of the successful candidate. Please apply to the specific position for which you which to be considered or both.


University of Iowa Hospitals & Clinics—recognized as one of the best hospitals in the United States—is Iowa's only comprehensive academic medical center and a regional referral center. Each day more than 12,000 employees, students, and volunteers work together to provide safe, quality health care and excellent service for our patients. Simply stated, our mission is: Changing Medicine. Changing Lives.®


Holden Comprehensive Cancer Center is Iowa's only NCI-designated comprehensive cancer center. The NCI designation recognized our cancer center, and its research scientist, physicians, and other health care professionals, for their roles in advancing cancer research that impacts on our ability to prevent, detect and treat our patients with cancer. Not just a floor, or a building, or even confined to a single college. Holden Comprehensive Cancer Center coordinates all cancer-related research, education, and patient care by faculty from 41 departments and six colleges, as well as UI Hospitals and Clinics and UI Children's Hospital.


Percent of Time: 100%
Pay Grade: 5A
Benefits Highlights: Regular salaried position located in Iowa City, Iowa Fringe benefit package including paid vacation; sick leave; health, dental, life and disability insurance options; and generous employer contributions into retirement plans For more information about Why Iowa?, click here Required Qualifications A Bachelors. in any discipline in biomedical sciences, or an equivalent combination of education and experience Experience (1-3 years) with immunological assays including flow cytometry, ELISA, multiplex ELISA, immunofluorescence, confocal microscopy, image analysis, and cell culture Attention to detail, strong organizational skills, and the ability to multitask several different projects Experience working in academic medical center or clinical research environment Proficiency in the development and optimization of assays/protocols Highly Desirable Qualifications Background in bioinformatics and analysis of large datasets Ph.D in biomedical sciences Experience in the development and optimization of multiplex spatial omics panels, especially for Canopy's CellScapeä platform Experience in the investigation of human immunology Adept knowledge of the following programs: Microsoft Office (PowerPoint, Excel, etc.), Prism, FlowJo, OMIQ, FACSDiva, SpectroFlo, ROSALIN Desirable Qualifications Knowledge of University of Iowa and University of Iowa Health Care policies, procedures, and regulations. Laboratory management experience Application Process: In order to be considered, applicants must upload a resume and cover letter (under submission relevant materials) that clearly address how they meet the listed required and desired qualifications of this position.
Job openings are posted for a minimum of 14 calendar days.
Successful candidates will be required to self-disclose any conviction history and will be subject to a criminal background check and credential/education verification.
References: Five professional references will be requested and required at a later step in the recruitment process
This position is not eligible for University sponsorship for employment authorization.
With additional questions, please reach out to Sarah Waldschmidt at