Principal Scientist - EnzymologyApply locations United States - California - San Diego
Time type Full time
Posted on Posted 3 Days Ago
Job requisition id 31094070
Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 114,000 colleagues serve people in more than 160 countries.
JOB DESCRIPTION:Working at Abbott At Abbott, you can do work that matters, grow, and learn, care for yourself and family, be your true self and live a full life. You'll also have access to:
Career development with an international company where you can grow the career you dream of!Free medical coverage for employees* via the Health Investment Plan (HIP) PPOAn excellent retirement savings plan with high employer contributionTuition reimbursement, the Freedom 2 Save student debt program and FreeU education benefit - an affordable and convenient path to getting a bachelor's degree.A company recognized as a great place to work in dozens of countries around the world and named one of the most admired companies in the world by Fortune.A company that is recognized as one of the best big companies to work for as well as a best place to work for diversity, working mothers, female executives, and scientists.The Opportunity This position works out of our San Diego, CA location in the Infectious Diseases Division. We are seeking an experienced Principal Scientist to oversee and conduct cutting-edge research in enzymology, to identify, characterize, optimize and develop proteins used for nucleic acid amplification and sample preparation technologies. Your expertise will be crucial in advancing our understanding of enzymatic processes and developing innovative solutions. You'll collaborate with cross-functional teams, establish protocols, and drive scientific excellence.
Responsibilities Lead protein characterization, optimization and development efforts, from design of experiments through laboratory studiesPerform kinetic, thermodynamic and structure-function studiesApply computational modeling to drive protein characterization and optimization effortsInitiate and oversee proteomics efforts in-house and via collaborationProvide cloning, protein expression, separation and purification expertiseImplement mutagenesis studies to help characterize and optimize proteins of interestDrive the introduction of new, optimized and/or modified proteins to improve product performanceDesign and implement procedures, processes and key performance indicators to monitor, characterize and QC proteinsProvide high level analysis of experimental resultsProvide written reports and oral presentations to executivesAbility to work as part of a team with excellent communication skillsExcellent communication and collaboration skillsRequired Qualifications Bachelor's Degree in Biochemistry/Biophysics/Protein chemistry, or a closely related field and 10 years of experience in a similar area.Preferred Qualifications Ph.D. in Biochemistry/Biophysics/Protein chemistry, or a closely related field and 10 years of experience.Minimum ten years of full-time laboratory experience in an industrial settingHands-on expertise using kinetic, thermodynamic and structure-function experimental approachesExpertise with computational modeling of proteins and protein/nucleic acid interactions to drive characterization of protein functionality and to drive the incorporations of protein modifications to improve/alter functionExtensive experience characterizing DNA/RNA interacting/binding proteinsExpertise in optimizing protein expression and purification methodsExpertise in developing, optimizing and performing in vitro enzymatic assaysExperience with high-throughput genetic/molecular screening a plusInventive, with ability to implement ideas in the laboratoryStrong problem-solving skills and the ability to analyze complex enzymatic processesExtensive hands-on experience driving the analytical, biological and functional characterization of proteinsExpertise in computational structure/function modeling of DNA/RNA binding proteinsTrack record of modifying and optimizing protein function to improve key performance characteristicsAbility to work as part of a team with excellent communication skills* Participants who complete a short wellness assessment qualify for FREE coverage in our HIP PPO medical plan. Free coverage applies in the next calendar year.
Learn more about our health and wellness benefits, which provide the security to help you and your family live full lives: www.abbottbenefits.com
Follow your career aspirations to Abbott for diverse opportunities with a company that can help you build your future and live your best life. Abbott is an Equal Opportunity Employer, committed to employee diversity.
The base pay for this position is $109,300.00 – $218,500.00
In specific locations, the pay range may vary from the range posted.
JOB FAMILY:Research and Discovery
DIVISION:ID Infectious Disease
LOCATION:United States > San Diego : 4545 Towne Center Court
WORK SHIFT:Standard
TRAVEL:No
MEDICAL SURVEILLANCE:No
SIGNIFICANT WORK ACTIVITIES:Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day), Continuous standing for prolonged periods (more than 2 consecutive hours in an 8 hour day), Keyboard use (greater or equal to 50% of the workday), Routine work with chemicals, Work in a clean room environment.
Abbott is an Equal Opportunity Employer of Minorities/Women/Individuals with Disabilities/Protected Veterans.
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