Site Name: USA - Pennsylvania - Upper Providence
Posted Date: Sep 5 2024
Are you looking to enhance your bioanalytical expertise by working for a global pharmaceutical company that allows you to leverage best in class LC-MS systems and technologies? If so, this Principal Scientist role is the ideal opportunity for you. At our world-class scientific hub in Upper Providence, Pennsylvania, our Biomarker and Bioanalytical Platforms (BBP) department currently has an exciting career opportunity for a talented individual with a passion for the analytical sciences and applying their skill set to addressing human disease.
As a Principal Scientist within the LC-MS Bioanalysis group, you will be responsible for the development and validation of assays to deliver PK and PD endpoints for clinical studies across the GSK portfolio. Data from this group is a key component to understanding molecules in the GSK pipeline and serves to make early and informed decisions for asset progression within the organization.
This role will provide you the opportunity to lead key activities to progress your career, these responsibilities include:
Responsible for developing LC-MS based bioanalytical assays to support clinical studies, delivering robust, high-quality data packages.Deliver, interpret, and communicate complex scientific data to project/program teams in a timely manner by performing data analysis, record keeping and reporting of results to agreed timelines.Drive the implementation of novel LC-MS based bioanalytical strategies for the measurement and characterization of drug, metabolites, and biomarkers in biological samples.Contribute to departmental strategy and capital investment discussions.Act as a Bioanalytical Subject Matter Expert for clinical study teams.Handle human biological samples and perform experimental work in accordance with HBSM, safety and data integrity guidelines.Contribute to the development of innovative LC/MS platforms internally and externally through conferences, publications, and working groups.Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals:
BS in Chemistry, Biochemistry or related discipline with 10 or more years of pharmaceutical industry bioanalysis experience.Experience with development of mass spectrometry-based methods to measure analytes from biological matrices.Experience troubleshooting methodological issues.Preferred Qualifications: If you have the following characteristics, it would be a plus:
PhD in Chemistry, Biochemistry or related discipline.MS in Chemistry, Biochemistry or related discipline with 5 or more years of pharmaceutical industry bioanalysis experience.Excellent computer skills for communication and report writing.Experience with analysis and reporting of preclinical or clinical PK data.Understanding of regulatory requirements for GxP analytical activities.Experience utilizing laboratory information management systems for daily job functions.Highly motivated team player with a proactive attitude, excellent organizational skills and a demonstrated ability to interact effectively within a multi-disciplinary team.Strong record of publications and presentations in novel biological or analytical mass spectrometry methods and applications.
#J-18808-Ljbffr
