Regeneron's Cell Culture Development Group within Preclinical Manufacturing and Process Development (PMPD) is looking for a motivated Process Development Associate II to work as part of the early stage development team to develop production processes of monoclonal antibodies in a non-GMP process development laboratory. In this role, they will perform studies at bench scale to screen top tier antibody candidates, conduct cell line selection, and perform medium and feed development in support of clinical or commercial manufacturing production.
A Typical Day in the Role of Process Development Associate II Might Look Like: Designing and developing cell culture studies in shaker flasks, single-use bioreactors (including AMBR250 system), and glass bench scale bioreactors (2L to 15L scale)Preparing media, feed, buffers, and reagentsOperating and maintaining bioreactor and analytical equipmentConducting statistical data analysisGenerating, managing, analyzing, and maintaining critical data in a highly organized mannerCoordinating and working with colleagues from other groups involved in the research process, including cell line development, bioreactor scale-up, purification, analytics, and manufacturing.Authoring development reports, entering electronic lab notebook entries, and reviewing manufacturing recordsActive involvement in technology transfer via written process transmittals, and by providing troubleshooting, process understanding, and on-site support to manufacturing production campaigns in Albany, NYThe position requires work on weekends and occasional travel to upstate NYThis Job May Be For You If: You have strong initiative and drive to complete ambitious tasks and learn new technologies.You can work both independently and within a team environment on multiple projects simultaneouslyYou contribute to lab equipment maintenance and safety to help create a safe, effective and efficient working environment.You possess strong organizational, communication, analytical, computer, and technical writing skills.You have a foundation of basic scientific/engineering knowledge obtained through academic training and/or experienceThis role requires a BS or MS in Chemical Engineering or Bio-related Engineering with 0-2 years of experience in a laboratory setting. Excellent verbal and written communication skills, and record keeping abilities to accurately record, analyze, and document development data generated. Additional Skills (preferred, but not required): Experience with mammalian cell culture; experience with developing fed-batch bioreactor processes including optimizing feeding strategies and evaluating different cell culture media and feed formulations; experience with ambr250; and experience with statistical design and analysis software (i.e., JMP).
Please include your GPA on your CV with your application.
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