Research Associate – Proteomics PlatformThe Broad Institute is an amazing place – we apply our deep knowledge of human genetics and exceptional technological armamentarium to empower a revolution in biomedicine and accelerate the pace at which the world understands biology and conquers disease. Through our partnerships with MIT, Harvard, and the Harvard teaching hospitals, we've become a worldwide hub of cutting-edge biomedical science. The Broad was founded to explore the applications of genomic and proteomic data and technologies to medicine, and now conducts research in infectious disease, cancer, and inherited disease along with basic research in the life sciences. This research is pushed forward through platforms such as the proteomics platform, centers of technological development that provide the tools and experience necessary to conduct experiments at a massive scale.
About the Position: The Broad Institute's Proteomics Group (Carr Lab) is an internationally-recognized leader in the field of biological mass spectrometry and proteomics. We are looking for highly motivated research associates to develop and apply state-of-the-art proteomics technology to address compelling questions in biology, chemistry, and clinical medicine. This is a rare opportunity to be a part of a dynamic interdisciplinary team of experts in protein biochemistry, proteomics, mass spectrometry, computational biology, and medicine. Working closely with senior scientific staff, you will be responsible for developing and implementing high-throughput sample preparation and analysis methods, including protein extraction, peptide, post-translationally modified peptide enrichment, chromatographic separation, and analysis by high-performance mass spectrometry, as well as data analysis and interpretation. Specifically, you will work on the development and application of cutting-edge discovery and targeted mass spectrometry-based technologies for the analysis of proteins and post-translational modifications. Additionally, the position will offer many opportunities to work on collaborative projects focused on cancer biology, neuroscience, and infectious disease, with a wide range of Broad, MIT, Harvard, and Harvard hospital-affiliated scientists with diverse backgrounds including biologists, clinicians, biochemists, chemists, and computational biologists.
In this position: You can make a difference in biomedicine – In studying the biological basis of cancer, neurological disease, infectious disease, and others you are laying the groundwork for future therapies that change lives. You will gain invaluable experience — This unique research opportunity will give you access to the best technologies and sharpest minds that biomedical research has to offer. At the Broad, we work closely with a wide network of physicians and scientists, we pioneer and use state-of-the-art technology, and we are empowered to pursue ambitious research – it is truly an experience that is unparalleled by any other biomedical research institution. Should you choose to, you will be well prepared to pursue a graduate or medical degree or expand your responsibilities within the lab over time. You will be supported in your efforts to learn and grow — Every week there are talks open to the Broad community on a variety of scientific topics, often hinging on results that have not yet been published. Many current RAs rave about the mentorship they have received from other Broadies and the variety of social events that create a fun, collaborative environment.
We are looking for candidates who have: The ability and desire to function in an open, interdisciplinary, and highly collaborative environment.Enthusiasm, self-motivation, and the ability to thrive in a fast-paced environment.Strong biochemistry laboratory skills are required, and experience with analytical separation techniques such as HPLC and mass spectrometry is highly desirable.Bachelor's degree in any life science, chemistry, bioengineering, chemical engineering, or a related field.1-4 years of undergraduate research experience, including working familiarity with basic laboratory techniques and principles of molecular biology.Exceptional organizational skills, critical thinking skills, and attention to detail.Excellent communication skills and the ability to interact professionally with all levels of staff and external contacts.The ability to work independently in response to guidance and direction and as part of a team.The ability to exercise judgment within defined practices, techniques, and standard operating procedures.A desire and willingness to learn, develop, and execute new assays or lab techniques.Interest in staying with the Broad for at least two years.
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