Scientist I, Early Discovery, Car T Cell Therapy (24214-U-670-Edis)

WHO WE ARE Arsenal Biosciences Inc. is a clinical-stage programmable cell therapy company engineering advanced CAR T-cell therapies for solid tumors. We are seeking a talented Scientist I, Early Discovery to work onsite based in our South San Francisco office.  ArsenalBio's mission and purpose is very clear: defeat cancer. With our programmable and computationally driven approach, our team is engineering medicines with the goal to attack cancer's inherent multifaceted nature and overcome the challenges of addressing solid tumors with cell therapy. Driven by a collective of diverse experts across multi-scientific disciplines as well as clinical and manufacturing expertise, we are united in our purpose to develop the optimal medicines for improving patients' lives. This means you'll have the opportunity to work with the best talent in the field of cell therapy, and be part of ONE TEAM advancing therapies for patients who need it most. We are on the lookout for a dynamic and innovative Scientist to drive early discovery efforts within our synthetic immunology team, dedicated to developing the next generation of CAR T cell therapies to transform cancer treatment. This role is ideal for someone with a strong background in immunology, synthetic biology, cellular biology, or cancer biology, paired with a creative mindset to introduce breakthrough ideas and tackle complex challenges head-on. The successful candidate will be a collaborative communicator, eager to engage across multiple disciplines, working seamlessly with a diverse team of experts. If you're passionate about advancing cell therapy in a fast-paced, cutting-edge environment, this position offers the perfect platform to make a significant impact. Join us to push the boundaries of science and innovation in the fight against cancer!

\n WHAT YOU'LL DODevelop novel methods to investigate and understand the biochemical and functional properties of specific receptor designsLead high-throughput screening of synthetic receptors for a portfolio of cell therapy applicationsWork closely with Molecular Biology experts to create DNA constructs and libraries that encode immune receptor domains. These will be derived from a range of design strategies—rational, semi-rational, and randomized approaches—to maximize diversity and functionality.Stay up-to-date with current research related to multiplexing readouts, synthetic immunology, and cell therapy, and apply these insights to our work. Collaborate with the ArsenalBio team to advance scientific and technical innovation in these areas.Summarize and synthesize data across experiments and present findings to all levels of the organizationOffer scientific leadership and mentorship to research associates while effectively organizing and prioritizing tasks across multiple projects.Work collaboratively and proactively with colleagues in automation, computational biology, NGS and discovery in a matrixed team structure WHO YOU AREPhD in immunology, molecular or cellular biology or a related field with 0-2  years of relevant experience, Masters with 5+ years experience, or Bachelors with 7+ years experience. Industry experience is preferred but not required. Have in-depth knowledge of CAR-T, SynNotch, and the synthetic receptor field.Experienced with primary cell culture and functional screening of human immune cellsExperienced in flow cytometry including developing flow cytometry panelsAbility to develop methods compatible with high throughput screening and collaborate with automation engineersFamiliarity with R or similar environments for pipelining of routine data analysisFamiliarity with cloning methods and working knowledge of NGS technologies and workflows is a plusOutstanding written and oral communication skills and the ability to organize and communicate complex data sets clearly and concisely to key stakeholders from diverse backgrounds Ability to multi-task and work in collaboration with peers within a fast-paced team environment with a positive outlook and high degree of self-motivation and organizationEntrepreneurial behaviors demonstrated by agility, accountability, transparency, resourcefulness, and ability to get things done effectively
\nBENEFITS AND PAY ArsenalBio has a generous and comprehensive benefits package that includes but is not limited to medical, dental, and vision as well as mental health resources, virtual and telehealth options, coaching, infertility treatment, parental leave and health savings accounts. We also offer flexible work schedules and flexible time off, which includes two extra "Arsenal Days of Rest" every quarter for employees to recharge.  Our people-first culture fosters a deep appreciation for humanity, both in the people we endeavor to serve as well as each other. We are proud to work for a company that is driven by diversity in experiences, ideas and interests, and one that empowers us in an environment that embraces both unity and inclusivity. We have robust tools to help employees take control of their career paths and grow into their best selves. ArsenalBio believes in investing in the well-being of our employees - both at work and at home, as our people are our greatest asset. They bring scientific talents in molecular biology, immunology, pharmacology, protein chemistry, computational biology, automation, genome engineering, software and other fields to make the future happen now. We are committed to hiring the best talent from diverse backgrounds. A diverse workforce engenders richness of thought, creativity and discovery. We invite individuals who embrace intellectual achievement to bring their unique personal and professional journeys and together we will build transformative cell therapies for cancer patients. We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. The estimated base salary for the preferred primary location of the San Francisco Bay area ranges from $110,200 - $135,000. Salary ranges for other locations may vary.  Base pay offered may vary based on job related knowledge, experience, education, and location.  In addition to these factors, we believe in the importance of pay equity and consider internal equity of our current employees as part of any final offer. To all recruitment agencies: ArsenalBio does not accept agency resumes. Please do not forward resumes to our jobs alias, or ArsenalBio employees. ArsenalBio is not responsible for any fees related to unsolicited resumes. Candidate Privacy Policy