We're in relentless pursuit of breakthroughs that change patients' lives. We innovate every day to make the world a healthier place.
To fully realize Pfizer's purpose – Breakthroughs that change patients' lives – we have established a clear set of expectations regarding "what" we need to achieve for patients and "how" we will go about achieving those goals.
Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues.
Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
What You Will Achieve As a Senior Associate Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. Your significant experience of applying knowledge of principles, concepts, and practices of the discipline will make you a critical member of the team. This laboratory-based position is in the Analytical Development group within Vaccine Research and Development. The primary function of this role is to develop analytical assays in support of the extensive vaccine portfolio. You will collaborate closely with scientists across the Early BioProcess Development (EBPD) to design and implement testing approaches for RNA product expression and potency of novel adjuvants. You will participate in regular vaccine development meetings and represent the group on multidisciplinary teams.
How You Will Achieve It Contribute to achievement of immediate work group goals and collaborate with other team members.Assist in the maintenance and renewal of laboratory instruments, systems or apparatus, and in the maintenance and continuous improvement of safe and effective working practices.Perform in-vitro expression analysis of mRNA Drug Substance (DS) and Drug Products (DP) for multiple RNA vaccine programs.Provide laboratory-based support for assay development, including ELISA and cell-based assays to support adjuvant development.Support sample testing for process development, formulation development, critical reagents characterization and on-going stability studies.Analyze data using appropriate statistical software, such as GraphPad Prism.Document experiments, data, and conclusions in an electronic lab notebook (ELN) contemporaneously.Contribute to authoring technical documents, including development reports, analytical lab methods, and method qualification reports.Review scientific and technical literature to stay current in the field.Present data in meetings within the department.Qualifications Must-Have Bachelor's degree in biological science, microbiology, immunology, or related fields with 3+ years relevant laboratory experience.Strong background and experience in mammalian cell culture, DNA and RNA transfection, and reporter cell assays.Experience with ELISA assay.Experience with in vitro expression and flow cytometry.Knowledge of innate and acquired immunity, with the ability to apply this knowledge to test novel adjuvants.Proficiency in analytical software, including GraphPad Prism and SoftMax.Proficiency in computer skills including Microsoft Word, PowerPoint, and Excel.Interact effectively with peers and leaders as part of a multidisciplinary team.Effective verbal and written communication skills.Nice-to-Have Experience with authoring development reports and lab methods.Experience in documenting experiments using Signals electronic lab notebook.PHYSICAL/MENTAL REQUIREMENTS Ability to work 40 hours/week in a laboratory setting.Ability to perform data analysis.Other Job Details: Last Date to Apply: November 11, 2024.Geography includes: USA - NY - Pearl River.Eligible for Relocation Package - NO
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