Senior Associate Scientist, Tumor Immunity--non PhDPOSITION SUMMARY Our Tumor Biology group develops biologic therapeutics that promote immune cell engagement with tumor cells in effort to eliminate cancer. As a member of this group, you will support these efforts and be a critical player in the group's mission by executing wet lab assays that will be used for proof-of-concept testing and lead molecule development. Your work will primarily focus on supporting biology line initiatives and will also involve collaborating with other functional lines in a matrix team environment.
POSITION RESPONSIBILITIES Execute cell-based functional and biochemical assays to select candidate molecules for clinical developmentPlan and execute ex vivo mouse tissue assays, such as multi-color flow cytometry, gene expression analyses, and mammalian cell cultureAnalyze, organize, and present results in small and large group meetingsRead relevant scientific literature to aid in experimental designBASIC QUALIFICATIONS B.S. degree in Biology or related discipline3+ years' of industry experience in immunology, cell biology and/or tumor biologyExperience planning and executing in vitro and/or in vivo/ex vivo experiments with some supervisionExperience with standard immunologic techniques including flow cytometry (8+ parameters)Experience with cancer cell line cultureStrong verbal and written communication skillsPREFERRED QUALIFICATIONS M.S. degree in Biology or related disciplineTechnical experience with immune cell-based functional assays including human/mouse T cell activation, proliferation, and cytotoxicity assays using T cell engagersExperience independently phenotyping human and mouse tumor associated T cells from primary human/mouse tumor samples using flow cytometry and conducting related analysesExperience with molecular techniques including ELISA, qRT-PCR, MSD, and CRISPR-CAS9 gene editingPHYSICAL/MENTAL REQUIREMENTS • Use of Personal Protective Equipment (PPE) in a BSL-2 laboratory
• Standard business office conditions; sitting, standing as appropriate
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS • Lifting, sitting, standing, walking, bending, repetitive pipetting, ability to perform mathematical calculations, ability to read, understand, and perform written protocols, and ability to perform moderately complex data analysis using Microsoft Excel, GraphPad Prism or other similar data analysis software.
• Routine off-hour and weekend schedule
Work Location Assignment: On Premise
The annual base salary for this position ranges from $64,600.00 to $107,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage.
EEO & Employment Eligibility Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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