Title: Scientist I (Downstream Process Development)
Location: San Carlos, CA
Duration: 06+ Months
Description:
The Process Development team is seeking a talented, highly motivated Scientist I to work on the purification of therapeutic antibody drug candidates from human and mouse immune repertoires. The successful candidate will provide downstream process development and material generation support within the company's Process Development team.
Primary responsibilities for role: Development, optimize, and scale-up purification processes for biologics candidates to support early stage development. Analyze and interpret data to drive technical understanding, meet project targets and objectives, problem solve, and make recommendations that drive efficiency, knowledge, and manage risk. Collaborate closely with other functional areas involved in antibody therapeutics development, including upstream process development, analytical development, project management, and cross-functional partners Work effectively with external collaborators and CROs Coordinate activities with functional groups and project teams Discuss experiments and data to project team members Develop, write, and review standard operating protocols and other technical documents May act as a lead for assigned projects or team. Mentor and train other technical staff. Knowledge, Skills, and Abilities: Experience in protein purification techniques, especially chromatography; antibody purification experience preferred Proficient in writing methods and operating AKTA chromatographic instruments (such as AKTA Avant, AKTA Purifier, AKTA Pure, AKTA Ready or similar) Strong scientific understanding and logical thinking Ability to train others in basic laboratory techniques and equipment operation Proficiency in analytical method development and analytical method validation Demonstrate flexibility and problem-solving activities. Education
Bachelor Experience 4+ years
Masters with 2+ years of experience
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